DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18480 and CPN2

DIOPT Version :9

Sequence 1:NP_001285960.1 Gene:CG18480 / 34920 FlyBaseID:FBgn0028518 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_001073982.3 Gene:CPN2 / 1370 HGNCID:2313 Length:545 Species:Homo sapiens


Alignment Length:235 Identity:60/235 - (25%)
Similarity:99/235 - (42%) Gaps:25/235 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 PKMWLGLKQILLYVGLLLCVLLQVCRSKTQSQMFCPTVCHCDLHAQRNRAVCSAKRLISANIEIP 73
            |..|      ||:..|||.         .:....||..|.|.:    ....||.:.|.:..::||
Human     3 PGAW------LLWTSLLLL---------ARPAQPCPMGCDCFV----QEVFCSDEELATVPLDIP 48

  Fly    74 TTVELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDLSYNRLEQID 138
            ...:.:.......||::..:|.:..:|..:...:..:.....|||..|.||..|:::.:....:.
Human    49 PYTKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLS 113

  Fly   139 EHILESNNQLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQ 203
            .:|..:...|..|.|..|.|..|.:|......:|.||:|:.:|:..|..:|...|..|:.|:|||
Human   114 TNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQ 178

  Fly   204 NLLLTLSPGDFHAPRNLASLNVEENPFNCDRALAKVATGL 243
            |||..|....||...:|.:|.:..|      ||:.:..|:
Human   179 NLLAQLPEELFHPLTSLQTLKLSNN------ALSGLPQGV 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18480NP_001285960.1 LRR_8 74..134 CDD:290566 11/59 (19%)
LRR_RI <76..230 CDD:238064 41/153 (27%)
leucine-rich repeat 76..99 CDD:275380 3/22 (14%)
leucine-rich repeat 100..123 CDD:275380 5/22 (23%)
LRR_8 122..182 CDD:290566 15/59 (25%)
leucine-rich repeat 124..147 CDD:275380 3/22 (14%)
leucine-rich repeat 148..171 CDD:275380 7/22 (32%)
LRR_8 170..230 CDD:290566 22/59 (37%)
leucine-rich repeat 172..195 CDD:275380 8/22 (36%)
leucine-rich repeat 196..219 CDD:275380 11/22 (50%)
CPN2NP_001073982.3 LRRNT 21..53 CDD:214470 9/35 (26%)
leucine-rich repeat 30..53 CDD:275380 5/26 (19%)
leucine-rich repeat 75..98 CDD:275380 5/22 (23%)
LRR 1 98..119 4/20 (20%)
leucine-rich repeat 99..122 CDD:275380 3/22 (14%)
LRR_8 121..181 CDD:290566 21/59 (36%)
LRR 2 122..143 7/20 (35%)
leucine-rich repeat 123..146 CDD:275380 7/22 (32%)
LRR 3 146..167 7/20 (35%)
leucine-rich repeat 147..170 CDD:275380 8/22 (36%)
LRR_RI 149..>356 CDD:238064 24/70 (34%)
LRR_8 169..229 CDD:290566 17/50 (34%)
LRR 4 170..191 10/20 (50%)
leucine-rich repeat 171..194 CDD:275380 11/22 (50%)
LRR 5 194..215 6/25 (24%)
leucine-rich repeat 195..218 CDD:275380 6/24 (25%)
LRR_8 218..277 CDD:290566
LRR 6 218..239
leucine-rich repeat 219..242 CDD:275380
LRR 7 242..263
leucine-rich repeat 243..266 CDD:275380
LRR 8 266..287
leucine-rich repeat 267..290 CDD:275380
LRR 9 290..311
leucine-rich repeat 291..314 CDD:275380
LRR_8 294..349 CDD:290566
LRR 10 314..335
leucine-rich repeat 315..338 CDD:275380
LRR 11 338..359
leucine-rich repeat 339..359 CDD:275380
LRR 12 362..383
leucine-rich repeat 363..382 CDD:275380
leucine-rich repeat 387..399 CDD:275378
LRRCT 395..446 CDD:214507
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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