Protein Alignment CG18480 and CHAD

DIOPT Version :10

• Sequence 1: NP_609761.1
• Gene: CG18480 / 34920
• FlyBaseID: FBgn0028518
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_054170751.1
• Gene: CHAD / 1101
• HGNCID: 1909
• Length: 440
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 92/345 - (26%)
• Similarity: 140/345 - (40%)
• Gaps: 65/345 - (18%)

  Fly    18 ILLYVGLLLCVLLQVCRSKTQSQMFCPTVCHCDLHAQRNRAVCSAKRLISANIEIPTTVE---LL 79
            :||.:|||..:|..:..        ||..|||  |:.....:|....|    .:||...|   ||
Human    87 LLLSLGLLAGLLPALAA--------CPQNCHC--HSDLQHVICDKVGL----QKIPKVSEKTKLL 137

  Fly    80 DLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDLSYNRLEQIDEHILES 144
            :|..|:...:..:||:...:|::|.|.|..|..:...||..|.:|.||.||:|.:..:.....:.
Human   138 NLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDD 202

  Fly   145 NNQLIHLNLEGNKLSTLGKGPILRSP--SLRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQNLLL 207
            ..:|.:|.|:.||::.|.:|  |.||  :|..|.|.|:::.:|..........||.|.|::|.|.
Human   203 LTELTYLYLDHNKVTELPRG--LLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALS 265

  Fly   208 TLSPG---------DFHAPRN---------LASLNVEE------NPFNC--DRALAKVATGLRQR 246
            :|.||         .||..||         |:.|.|.|      ||...  |.|.......|.
Human   266 SLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLE-- 328

  Fly   247 GVAIFMSNCMEEEVQD------------HQDDAEAVNFPNKNEKFESMEYLEPSTRGPQSVLSVW 299
              .:::.|...|:..|            |.::......|: |..|:|:|.| ..|..|.......
Human   329 --TLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS-NFPFDSLETL-ALTNNPWKCTCQL 389

  Fly   300 RDLDSSEEQNSSQDDEQMSS 319
            |.|....|..:|:.|...:|
Human   390 RGLRRWLEAKASRPDATCAS 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_609761.1	LRR	<66..>230	CDD:443914	56/192 (29%)
		leucine-rich repeat	76..99	CDD:275380	7/25 (28%)
		leucine-rich repeat	100..123	CDD:275380	8/22 (36%)
		leucine-rich repeat	124..147	CDD:275380	6/22 (27%)
		leucine-rich repeat	148..171	CDD:275380	10/24 (42%)
		leucine-rich repeat	172..195	CDD:275380	5/22 (23%)
		leucine-rich repeat	196..219	CDD:275380	11/31 (35%)
CHAD	XP_054170751.1	LRRNT	104..130	CDD:396168	10/31 (32%)
		LRR	131..>382	CDD:443914	69/258 (27%)
		leucine-rich repeat	134..157	CDD:275380	6/22 (27%)
		leucine-rich repeat	158..181	CDD:275380	8/22 (36%)
		leucine-rich repeat	182..205	CDD:275380	6/22 (27%)
		leucine-rich repeat	206..229	CDD:275380	10/24 (42%)
		leucine-rich repeat	230..253	CDD:275380	5/22 (23%)
		leucine-rich repeat	254..277	CDD:275380	9/22 (41%)
		leucine-rich repeat	278..301	CDD:275380	6/22 (27%)
		leucine-rich repeat	302..325	CDD:275380	5/22 (23%)
		leucine-rich repeat	327..350	CDD:275380	4/26 (15%)
		leucine-rich repeat	351..373	CDD:275380	4/22 (18%)
		LRRCT	381..428	CDD:214507	7/29 (24%)