DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7631 and TLL2

DIOPT Version :9

Sequence 1:NP_609760.1 Gene:CG7631 / 34919 FlyBaseID:FBgn0028945 Length:254 Species:Drosophila melanogaster
Sequence 2:NP_036597.1 Gene:TLL2 / 7093 HGNCID:11844 Length:1015 Species:Homo sapiens


Alignment Length:209 Identity:71/209 - (33%)
Similarity:104/209 - (49%) Gaps:13/209 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 RNGQLSETRR-WPNATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPST 112
            |....|.|.| ||...:||.|...|........|..|:..|..:|:.|:.. .|||:::.....|
Human   148 RRATTSRTERIWPGGVIPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIER-TDEESFIVFSYRT 211

  Fly   113 SGCSSKVGYQPGERTVKLKPGSLDTG--CFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENI 175
            .||.|.||.:.|      .|.::..|  |.|.|.:.|||.|.:||.|:...|:||:.|.|:.|||
Human   212 CGCCSYVGRRGG------GPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENI 270

  Fly   176 SEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFS--INGEATIVALNPEG-QEQMGQRLMMS 237
            ..|.|.||:|.|..||....:.||:.||:||:...||  :..:..:...:..| :..:|||:.:|
Human   271 QPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLS 335

  Fly   238 DTDVKRLNTMYKCP 251
            ..|:.:...:||||
Human   336 QGDIAQARKLYKCP 349

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7631NP_609760.1 Astacin 57..251 CDD:279708 66/199 (33%)
ZnMc_astacin_like 61..248 CDD:239807 61/191 (32%)
TLL2NP_036597.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..49
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 88..130
ZnMc_BMP1_TLD 150..349 CDD:239808 68/205 (33%)
Astacin 157..350 CDD:279708 68/200 (34%)
CUB 351..460 CDD:278839
CUB 464..573 CDD:278839
FXa_inhibition 584..616 CDD:291342
CUB 620..729 CDD:278839
FXa_inhibition 736..771 CDD:291342
CUB 776..885 CDD:278839
CUB 889..1002 CDD:278839
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S3579
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.760

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