DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and Tll1

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001099551.1	Gene:	Tll1 / 678743	RGDID:	1306120	Length:	1013	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	69/204 - (33%)
Similarity:	100/204 - (49%)	Gaps:	13/204 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 SETRR-WPNATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSS 117
            |.|.| ||...:||.|...|........|..|:..|..:|:.|... .|||:|:.......||.|
  Rat   151 SRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTER-SDEESYIVFTYRPCGCCS 214

  Fly   118 KVGYQ-PGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEK 181
            .||.: .|.:.:     |:...|.|.|.:.|||.|.:||.|:...|:||..|.|:.|||..|.|.
  Rat   215 YVGRRGNGPQAI-----SIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEY 274

  Fly   182 NFVKYEEDEVGDFDQPYDYGSILHYSSLAFSING---EATIVALNPEG-QEQMGQRLMMSDTDVK 242
            ||:|.|..||....:.||:.||:||:...|| .|   :..:.:.:..| :..:|||..:|..|:.
  Rat   275 NFLKMEPGEVNSLGERYDFDSIMHYARNTFS-RGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIA 338

  Fly   243 RLNTMYKCP 251
            :...:|:||
  Rat   339 QARKLYRCP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	65/199 (33%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	61/191 (32%)
Tll1	NP_001099551.1	ZnMc_BMP1_TLD	148..347	CDD:239808	67/202 (33%)
		Astacin	155..348	CDD:279708	67/200 (34%)
		CUB	349..458	CDD:278839
		CUB	462..571	CDD:278839
		FXa_inhibition	582..614	CDD:291342
		CUB	618..727	CDD:278839
		FXa_inhibition	734..769	CDD:291342
		CUB	774..883	CDD:278839
		CUB	887..1000	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810