DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and astl2c

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001037864.1	Gene:	astl2c / 594901	XenbaseID:	XB-GENE-6449741	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	82/272 - (30%)
Similarity:	125/272 - (45%)	Gaps:	39/272 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FQLFLLGTLCSGIFPAPF-NTHYDETDPELTAG------------------YFQGDMDVDYARNG 51
            |.||    :|:..||... ..|.::.|.|:...                  :.|||:...::|:.
Frog    11 FGLF----VCATSFPIQIVFPHVEQNDTEVPDNDDDVFGRILRANKGKRNFHVQGDIAHKFSRSA 71

  Fly    52 QLSETRRWPN-----ATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPS 111
            ...:...||.     ..|||.||.::.......|...||.....:|::|:| ..||::|:.:.|
Frog    72 INCKECLWPKDSNGIVNVPYTISSDYSQNEASLIMAAMQEFATLTCVQFIP-QTDEDDYIAIQP- 134

  Fly   112 TSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENIS 176
            ..||.|.:|...|.:.|.|..|    ||...|.|||||.|.|||.|:....:||.:|.|..:.||
Frog   135 LDGCWSYIGVNGGAQQVSLGKG----GCIYYGVIQHELNHVLGFVHEHSRSDRDNYVHINYQYIS 195

  Fly   177 EGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFS-INGEATIVALNPEGQEQMGQRLMMSDTD 240
            ..:...|.|.:.|.:|   ..|||.|::||...::| ..|:.|||.: |.....:|||..:|..|
Frog   196 PDNIAFFDKKDTDNLG---LEYDYSSVMHYPGYSYSNTTGKNTIVPI-PNANVPIGQRYGLSTLD 256

  Fly   241 VKRLNTMYKCPI 252
            |.::|.:|:|.:
Frog   257 VSKINRLYQCDV 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	68/199 (34%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	65/192 (34%)
astl2c	NP_001037864.1	ZnMc_hatching_enzyme	84..266	CDD:239810	66/191 (35%)
		Astacin	89..266	CDD:279708	66/186 (35%)
		CUB	270..380	CDD:238001
		CUB	383..495	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000