DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and cuzd1.2

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_021323075.1	Gene:	cuzd1.2 / 555768	ZFINID:	ZDB-GENE-131119-30	Length:	718	Species:	Danio rerio

Alignment Length:	269	Identity:	54/269 - (20%)
Similarity:	72/269 - (26%)	Gaps:	124/269 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 DYARNGQLSETRRWPNATVPYRISEEFDAPHVEYIKLGMQFIEYS----SCIRFVPAD----EDE 102
            ||  |....:|..||..|         |.|...| ..|     |:    ||..|...|    .|.
Zfish   159 DY--NSYCFQTTTWPTTT---------DIPSCMY-NCG-----YNPGSCSCTDFCQRDGNCCPDY 206

  Fly   103 ENYLFVLPSTS----------GCSSKVGYQPG-----------------------ERTVKLKPGS 134
            |.|.....:|:          .|....||..|                       |.|
Zfish   207 EAYCSETTTTTAFEPDTTEILSCMYNCGYNLGGCSCTEFCRSYGNCCPDYEAYCSETT------- 264

  Fly   135 LDTGCFKLGTIQHELLHTLGFHHQQCSPNRD-EFVKI--------------VEENISEGHEKNFV 184
              |..|:..|..|..::..|:....||..|| .:..|              :.::.:|.|
Zfish   265 --TTTFEPDTTAHSCMYNCGYDLGSCSCARDCHYYDICCPDYDSHCPSYTTLRDSTTELH----- 322

  Fly   185 KYEEDE---------VGDFDQPYDYGSILH-------YSSLAFSINGEATIVALNPEGQEQMGQR 233
             |.|..         .|.|..| :|.|..|       |.|                   .|.|||
Zfish   323 -YTESHPKCGGHLYGAGLFSTP-NYPSYYHDNAYCVWYLS-------------------AQQGQR 366

  Fly   234 LMMSDTDVK 242
            :.::..||:
Zfish   367 IFLTFADVQ 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	50/258 (19%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	48/254 (19%)
cuzd1.2	XP_021323075.1	CUB	21..127	CDD:238001
		Somatomedin_B	131..164	CDD:307259	3/6 (50%)
		Somatomedin_B	175..214	CDD:321959	12/44 (27%)
		Somatomedin_B	<239..260	CDD:307259	0/20 (0%)
		CUB	330..439	CDD:238001	14/66 (21%)
		ZP	450..694	CDD:214579
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900