DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and tll1

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001008039.1	Gene:	tll1 / 493401	XenbaseID:	XB-GENE-479941	Length:	495	Species:	Xenopus tropicalis

Alignment Length:	255	Identity:	83/255 - (32%)
Similarity:	120/255 - (47%)	Gaps:	32/255 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SGIFPAPFNTHYDETDPELTAGY--------------FQGDMDVDYARNGQLSETRRWPNAT--- 63
            ||..|.|  ...|..||.....|              ..||:.:...||........||.::
Frog    23 SGTLPTP--KSQDGKDPADNNLYTDIMKANQKSKKLRIHGDIALKTDRNAINCTECLWPKSSDGF 85

  Fly    64 --VPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQPGER 126
              |||.:|.::....|..|...|:..|..:|::|.|. ..|::|| .:.|..||.|.:||..|.:
Frog    86 VYVPYTVSSDYSQDEVNAITTAMKEYEGLTCVQFTPW-TGEDDYL-AIQSLDGCWSYIGYYGGSQ 148

  Fly   127 TVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEV 191
            .|.|..|.    |...|.:||||.|.|||:|:....:||::|.|:.:.||..:..||.|...:.:
Frog   149 AVSLLKGF----CAYNGGVQHELNHALGFYHEHNRSDRDDYVTIMYQYISPENIGNFDKISTNNL 209

  Fly   192 GDFDQPYDYGSILHYSSLAFS-INGEATIVALNPEGQEQMGQRLMMSDTDVKRLNTMYKC 250
            |   ..|||.|||||:..||| .:|:.|||. :|.....:||...:|:.||.::|.:|.|
Frog   210 G---VDYDYSSILHYAGNAFSNTSGQNTIVP-HPNPNVPIGQSYGLSNLDVLKINRLYGC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	71/200 (36%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	67/192 (35%)
tll1	NP_001008039.1	ZnMc_hatching_enzyme	83..265	CDD:239810	68/191 (36%)
		CUB	269..379	CDD:238001
		CUB	382..494	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910