DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and tll1

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_571085.1	Gene:	tll1 / 474335	ZFINID:	ZDB-GENE-041020-1	Length:	1022	Species:	Danio rerio

Alignment Length:	220	Identity:	72/220 - (32%)
Similarity:	107/220 - (48%)	Gaps:	20/220 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VDYARNGQLSETRR--------WPNATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADED 101
            |:.|||.:....|.        ||...:||.|...|.......:|..|:..|..:|:.|: ...|
Zfish   144 VNSARNVKSRVPRAATSRAEKIWPGGVIPYVIGGNFTGSQRAMLKQAMRHWEKQTCVTFI-EKTD 207

  Fly   102 EENYLFVLPSTSGCSSKVGYQ-PGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRD 165
            ||:|:.......||.|.||.: .|.:.:     |:...|.|.|.:.|||.|.:||.|:...|:||
Zfish   208 EESYIVFTYRPCGCCSYVGRRGNGPQAI-----SIGKNCDKFGIVVHELGHVIGFWHEHTRPDRD 267

  Fly   166 EFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSINGE--ATIVALNPEG-- 226
            :.|.|:.:||..|.|.||:|.|..:|....:|||:.||:||:...|| .|.  .||:....|.
Zfish   268 DHVTIIRDNIQPGQEYNFIKMEPGDVNSLGEPYDFDSIMHYARNTFS-RGMFLDTILPSRDENGV 331

  Fly   227 QEQMGQRLMMSDTDVKRLNTMYKCP 251
            :..:|||..:|..|:.:...:|:||
Zfish   332 RPAIGQRTRLSKGDISQAKKLYRCP 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	66/206 (32%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	62/191 (32%)
tll1	NP_571085.1	ZnMc_BMP1_TLD	157..356	CDD:239808	65/205 (32%)
		Astacin	164..357	CDD:279708	67/200 (34%)
		CUB	358..467	CDD:278839
		CUB	471..580	CDD:278839
		FXa_inhibition	591..623	CDD:291342
		CUB	627..736	CDD:278839
		FXa_inhibition	743..778	CDD:291342
		CUB	783..892	CDD:278839
		CUB	896..1009	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810