DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and mep1bb

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_009294699.1	Gene:	mep1bb / 327586	ZFINID:	ZDB-GENE-030131-5797	Length:	774	Species:	Danio rerio

Alignment Length:	214	Identity:	79/214 - (36%)
Similarity:	115/214 - (53%)	Gaps:	9/214 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FQGDM--DVDYARNGQLSETRRWPNATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADED 101
            |:||:  |....||..:.|..|||. |:||...::.:......|....:.....:||.:.|. ..
Zfish    61 FEGDILYDETLGRNSIIGEEYRWPK-TIPYYFEDDLEINAKGVILKAFEQYRLKTCIDYKPW-TG 123

  Fly   102 EENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDE 166
            ||||:.|... :||.|.|    |.|.|..:..|:.:||.::.||:||.||.|||.|:|...:||:
Zfish   124 EENYISVFKG-NGCFSSV----GNRRVGRQTLSIGSGCDRIATIEHEFLHALGFWHEQSRSDRDD 183

  Fly   167 FVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSINGEATIVALNPEGQEQMG 231
            :|.|:.:.|:||.|.||.||.:......:.||||.|::|||..||....|.||:...|.....:|
Zfish   184 YVSIMWDRITEGKEHNFNKYNDSSSSALNVPYDYSSMMHYSQKAFQSGSEPTIITRIPAFSSVIG 248

  Fly   232 QRLMMSDTDVKRLNTMYKC 250
            ||:..||:|:.:||.:|.|
Zfish   249 QRMEFSDSDLLKLNRLYNC 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	72/194 (37%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	67/186 (36%)
mep1bb	XP_009294699.1	ZnMc	39..267	CDD:294052	78/212 (37%)
		Astacin	81..269	CDD:279708	72/194 (37%)
		MAM	277..441	CDD:279023
		MAM	277..440	CDD:99706
		MATH	440..608	CDD:295307
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910