DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and Adgrg6

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_218313.7	Gene:	Adgrg6 / 308376	RGDID:	1308551	Length:	1248	Species:	Rattus norvegicus

Alignment Length:	233	Identity:	55/233 - (23%)
Similarity:	76/233 - (32%)	Gaps:	46/233 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WFQ----LFLLGTLCSGIFPAPF----NTHYDETDPELTAGYFQGD-MDVDYARNGQLSETRRWP 60
            |.|    |..|..||...||.|.    |.....::|   :|.|... ...||......|.|.|.|
  Rat    13 WRQKSSTLLFLFALCVACFPLPVWGCGNCRLVLSNP---SGTFTSPCYPNDYPNTQSCSWTLRAP 74

  Fly    61 NATVPYRISEEFD---APHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCS--SKVG 120
            ...:......:||   ||:..|..|.:              |..|....|...:..|.|  |.|
  Rat    75 TGYIIQITFNDFDIEEAPNCIYDSLSL--------------DNGESQTKFCGATAKGLSFNSSV- 124

  Fly   121 YQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQ--CSPNRDEFVKIVEENISEGHEKNF 183
               .|..|..   |.|....|.|.....:...:...:|:  .....|.:...|.::||....|.|
  Rat   125 ---NEMHVSF---SSDFSIQKKGFNASYIRVAVSLRNQKVILPQTLDAYQVSVAKSISIPELKAF 183

  Fly   184 -VKYEEDEVGDFDQ-----PYDYGSILHYSSLAFSING 215
             :.:|..:||:.|.     .|...|:....||..:.||
  Rat   184 TLCFEASKVGNEDDDWTAFSYSDKSLTQLLSLEKANNG 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	38/172 (22%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	36/168 (21%)
Adgrg6	XP_218313.7	CUB	38..146	CDD:238001	29/131 (22%)
		LamG	178..337	CDD:304605	12/44 (27%)
		GPS	799..844	CDD:280071
		7tm_4	861..1108	CDD:304433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900