DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and Astl

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001099974.1	Gene:	Astl / 296129	RGDID:	1562279	Length:	436	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	78/270 - (28%)
Similarity:	116/270 - (42%)	Gaps:	52/270 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 CSGI----FPAPFNTHYDETDPELTAGYFQGDMDVDYARNGQLSE-------------------- 55
            |||:    .|..|.       ||  ......|.|:.....|.:||
  Rat    30 CSGVCSTSVPEGFT-------PE--GSRVSQDKDIPAINQGLISEETPESSFLVEGDIIRPSPFR 85

  Fly    56 -----TRRWPNAT-----VPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLP 110
                 ..:||...     :|:.:|.::|.|..:.|.......|..:||||| |...:.:::.:||
  Rat    86 LLSVTNNKWPKGVDGIVEIPFLLSSKYDEPSRQVIMEAFAEFERFTCIRFV-AYRGQRDFVSILP 149

  Fly   111 STSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENI 175
             .:||.|.||...|.:.|.|.|..|..|   .|.:.|||:|.|||.|:....:||.::::....|
  Rat   150 -MAGCFSGVGRSGGMQVVSLAPTCLQKG---RGIVLHELMHVLGFWHEHSRADRDRYIRVNWNEI 210

  Fly   176 SEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSINGEATIVALNPEGQEQMGQRLMMSDTD 240
            ..|.|.||:|...   .:...||||.|::||...|||..|:.||:.| ......:|||..:|.:|
  Rat   211 LPGFEINFIKSRN---SNMLAPYDYSSVMHYGRFAFSWRGQPTIIPL-WTSSVHIGQRWNLSTSD 271

  Fly   241 VKRLNTMYKC 250
            :.|:..:|.|
  Rat   272 ITRVCRLYSC 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	66/199 (33%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	62/191 (32%)
Astl	NP_001099974.1	Astacin	92..283	CDD:279708	66/199 (33%)
		ZnMc	99..281	CDD:294052	63/190 (33%)
		ImpA_N	<305..420	CDD:303075
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920