DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7631 and nas-30

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_490795.5	Gene:	nas-30 / 190803	WormBaseID:	WBGene00003548	Length:	741	Species:	Caenorhabditis elegans

Alignment Length:	263	Identity:	80/263 - (30%)
Similarity:	126/263 - (47%)	Gaps:	38/263 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AP-FNTHYDETD----PELTAGYFQGDM------------DVDYARNGQLSETR--------RWP 60
            || ...|.|.|:    ..||...|:.||            ....|||....:.|        ||
Worm   270 APMLQAHRDGTELGANRALTNKLFESDMVLTVKQMKAIVLAAQEARNPHGRKKRKVITGSVYRW- 333

  Fly    61 NATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQPGE 125
            .:.:|:|. :..||...:.|:.|:...|..:|:|:......::..:|.  ..|||.|.||...|.
Worm   334 KSVIPFRF-KGGDAKWKKLIREGLGLWEKETCVRWSENGPGKDYVIFF--RGSGCYSSVGRTGGS 395

  Fly   126 RTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDE 190
            :.:     |:..||...|.:.||:.|:|||.|:|..|:||:::.:.::.|.:|.:.||.|...:|
Worm   396 QLI-----SIGYGCEDKGIVAHEVGHSLGFWHEQSRPDRDDYIHLRKDWIIKGTDGNFEKRSWEE 455

  Fly   191 VGDFDQPYDYGSILHYSSLAFSIN-GEATIVALNPEGQEQMGQRLMMSDTDVKRLNTMY---KCP 251
            :.|...|||.||::||.|.||:.: .:.||...:...|..:|||..:|..|||::|.:|   .||
Worm   456 IEDMGVPYDVGSVMHYGSNAFTKDWDQITIETKDSRYQGTIGQRQKLSFIDVKQVNRLYCNSVCP 520

  Fly   252 IQL 254
            :.|
Worm   521 VAL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	64/205 (31%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	60/187 (32%)
nas-30	NP_490795.5	ZnMc_astacin_like	336..514	CDD:239807	60/185 (32%)
nas-30	NP_490795.5	CUB	564..648	CDD:412131
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920