DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and nas-27

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_493926.2	Gene:	nas-27 / 188809	WormBaseID:	WBGene00003545	Length:	428	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	68/224 - (30%)
Similarity:	105/224 - (46%)	Gaps:	25/224 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FQGDMDV--DYARNGQLSETRRWPNATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADED 101
            :|||:.|  ..||...:.:..:.....:||.....|.:...:.:...|||....:|:.|
Worm    44 YQGDIAVVKSRARRAVIRQKHKKWKLPMPYSFDRNFPSRSRQRVLEAMQFWSEKTCVTF------ 102

  Fly   102 EENYLFVLPSTS-----GCSSKVGYQPGERTVKLKPGSLDTGC----FKLGTIQHELLHTLGFHH 157
            .|| .:|.|..|     ||.|.||.||..|...|   ||:..|    |   .:.||:.|||||:|
Worm   103 HEN-RYVYPHVSIFEGNGCWSFVGKQPSLREQSL---SLERSCTDHTF---VVAHEIAHTLGFYH 160

  Fly   158 QQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSIN-GEATIVA 221
            :....:||:|:.|...|::......|.|..|.::...:..|:|||::|||...|::| ....|.|
Worm   161 EHARGDRDQFISIDYSNVNPNLTFAFAKESEKQLDHQEAAYEYGSVMHYSVDQFAVNTNRPVIYA 225

  Fly   222 LNPEGQEQMGQRLMMSDTDVKRLNTMYKC 250
            .:.:..:.||.|:..:..||.|:|.:|.|
Worm   226 RDQKFAQAMGNRMRATFQDVSRMNVLYNC 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	62/204 (30%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	60/196 (31%)
nas-27	NP_493926.2	Astacin	65..254	CDD:279708	61/201 (30%)
		ZnMc_astacin_like	70..252	CDD:239807	60/194 (31%)
		CUB	334..410	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920