DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and nas-33

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_509086.2	Gene:	nas-33 / 186987	WormBaseID:	WBGene00003551	Length:	644	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	75/228 - (32%)
Similarity:	111/228 - (48%)	Gaps:	20/228 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ELTAGYFQGDMDV------DYARNGQLSETRRWPNAT-----VPYRISEEFDAPHVEYIKLGMQF 86
            ::.|..|:.||.:      ..|:||...:.:...|.|     :|||..:. |......|..|::.
Worm   164 KIAAVMFESDMALTVSQMNKVAQNGFRVKRKMNLNGTTWSRNIPYRFLDT-DGNWQSQITNGLRH 227

  Fly    87 IEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLH 151
            .|.::|||| ..:....:|| |.....||.|.||...|.:.:     |:..||..||.|.||:.|
Worm   228 YERNTCIRF-SLNGGGSDYL-VFSKGEGCYSSVGRLGGPQEI-----SIGDGCETLGIITHEVGH 285

  Fly   152 TLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSINGE 216
            .|||.|:|..|.||.:|:|..:|...|.|..|.|....||.::..||||||::||...:||.:..
Worm   286 ALGFWHEQARPERDSYVRINRQNAINGLEGQFDKRSWSEVNEYSLPYDYGSVMHYGPKSFSKSST 350

  Fly   217 A-TIVALNPEGQEQMGQRLMMSDTDVKRLNTMY 248
            . |:..::|.....:|.|:..|..|:|.|||.:
Worm   351 MNTVEPVDPAFINTIGNRVEPSFLDLKLLNTAF 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	68/198 (34%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	68/192 (35%)
nas-33	NP_509086.2	Astacin	200..386	CDD:279708	67/192 (35%)
		ZnMc_astacin_like	203..381	CDD:239807	64/185 (35%)
		CUB	442..527	CDD:294042
		TSP1	553..595	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920