DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and nas-31

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001023994.1	Gene:	nas-31 / 186493	WormBaseID:	WBGene00003549	Length:	611	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	71/239 - (29%)
Similarity:	104/239 - (43%)	Gaps:	39/239 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FQGDMDV------------DYARNGQLSETRR-------WPNAT----VPYRISEEFDAPHVEYI 80
            :||||.:            |.......|..||       :|:.|    |.|..........|:..
Worm   127 YQGDMVLTDDQIATILEARDETTVSTASRARRQAYRDRYYPSTTWGSSVYYYYDRTATPKIVKAF 191

  Fly    81 KLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTI 145
            :..:.|.:..:||..:.: ....|.:.|... .||.|.||...|.:.:     ||.|||.:.||.
Worm   192 EQAVAFWQNVTCINIMQS-STAINRIRVFKG-QGCYSYVGRISGVQDL-----SLGTGCEEFGTA 249

  Fly   146 QHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLA 210
            .|||.|.|||.|.|...:||.::.|...||...:.:.|.|...:...::..|||||||:.|.:.:
Worm   250 AHELGHALGFFHTQSRYDRDNYISINYANIDPSYVEQFDKETSNTNFNYGMPYDYGSIMQYGATS 314

  Fly   211 FSINGEATIVALNPEGQEQMGQRLMMSD----TDVKRLNTMYKC 250
            .|.|.:||::|.:.|.|:.||     ||    .|:..:|..|||
Worm   315 ASSNDKATMIARDTEYQDTMG-----SDFVGFYDISMMNEHYKC 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	65/209 (31%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	59/194 (30%)
nas-31	NP_001023994.1	Astacin	169..355	CDD:279708	62/197 (31%)
		ZnMc_astacin_like	175..351	CDD:239807	58/187 (31%)
		ShKT	532..564	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010