DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and nas-28

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_498342.3	Gene:	nas-28 / 185658	WormBaseID:	WBGene00003546	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	73/250 - (29%)
Similarity:	118/250 - (47%)	Gaps:	32/250 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 YDETDPELTAGYFQGDMDVDYAR---------NGQLSETRR--------WPNATVP--YRISEEF 72
            ::|.:.::....|:.|:.::..:         ||.....|:        | :.:||  |:...:.
Worm    81 FEELNQDINEYTFESDIMLNEKQAKHIATAIENGNYRSKRQAIVDTTNFW-SVSVPIFYQFDTKL 144

  Fly    73 DAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQ---PGERTVKLKPGS 134
            .|.::..::..:||...:||:.| ..|.:.:|.|| |.|..||.|.||.|   |.:..      |
Worm   145 SATNIANVRKAIQFWNDNSCLSF-KEDNNAKNRLF-LSSAGGCWSYVGKQVDMPYQMV------S 201

  Fly   135 LDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYD 199
            :...|...||..|||:|.:||.|||...:||.:|.:...||......||.|...|:....:.|||
Worm   202 VGPNCDTFGTATHELMHAIGFWHQQSRADRDNYVYVDFSNIIPSQAYNFQKMAVDQAQLLNLPYD 266

  Fly   200 YGSILHYSSLAFSI-NGEATIVALNPEGQEQMGQRLMMSDTDVKRLNTMYKCPIQ 253
            |||::.|...||:: :.:.||:|.....|..||||...:.:|:..:|.:|.|..|
Worm   267 YGSVMQYYPYAFAVDSSKYTILAKENGFQNSMGQREAPAFSDIIGVNKLYNCTSQ 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	66/207 (32%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	63/192 (33%)
nas-28	NP_498342.3	Astacin	135..320	CDD:279708	64/192 (33%)
		ZnMc_astacin_like	135..316	CDD:239807	62/188 (33%)
		CUB	393..480	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920