DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7631 and nas-4

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001254938.1	Gene:	nas-4 / 182259	WormBaseID:	WBGene00003523	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	89/259 - (34%)
Similarity:	139/259 - (53%)	Gaps:	28/259 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 TLCSGIFPAPFNTHYD--------ETDPELTAGYFQGDMDVDYAR-----NGQLSET------RR 58
            ||....|.:..:..||        :.||.: ..|.:||:.::..:     |.:|...      ||
Worm    40 TLNDADFHSDLHQRYDLQTLGIKVKDDPTI-GNYSEGDILLESPKKFVEENNKLGRNAIKQIYRR 103

  Fly    59 WPNATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDE-ENYLFVLPSTSGCSSKVGYQ 122
            |||..:||.:|.::.:.....|...|......:|::||..|..: .:||::.|. .||.|.||..
Worm   104 WPNNEIPYTLSSQYGSYARSVIANAMNEYHTKTCVKFVARDPSKHHDYLWIHPD-EGCYSLVGKT 167

  Fly   123 PGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYE 187
            .|:     :|.|||:||.::|||.|||:|.:||.|:|...:||.::.:|.:|:..|.:..|.||.
Worm   168 GGK-----QPVSLDSGCIQVGTIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYN 227

  Fly   188 EDEVGDFDQPYDYGSILHYSSLAFSINGEATIVALNPEGQEQMGQRLMMSDTDVKRLNTMYKCP 251
            .:.:...|:||||.||:||...|||.:|:.|:|. ...|.|:||||:..||.||:::|.:|.||
Worm   228 LNVISHLDEPYDYASIMHYGPYAFSGSGKKTLVP-KKSGSERMGQRVKFSDIDVRKINKLYNCP 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	75/194 (39%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	70/187 (37%)
nas-4	NP_001254938.1	Astacin	102..290	CDD:279708	75/194 (39%)
nas-4	NP_001254938.1	ZnMc_astacin_like	106..287	CDD:239807	70/187 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49330
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930