DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and nas-10

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001257126.1	Gene:	nas-10 / 181287	WormBaseID:	WBGene00003529	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	68/253 - (26%)
Similarity:	106/253 - (41%)	Gaps:	33/253 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FQLFLLGTLCSGIFPAPFNTHYDETDPELTAGYFQGDMDVDYARNGQLSETRRWPNAT-VPYRIS 69
            |.|..||....|..|.|     .....:..:.:|:.::            .::||:.: :||...
Worm   269 FMLNELGKGGEGAIPMP-----GSAKAKRASIFFEQNL------------IQKWPSTSPIPYTFD 316

  Fly    70 EEFDAPHVEYIKLGMQFIEYSSCIRF----VPADEDEENYLFVLPSTSGCS-SKVGYQPGERTVK 129
            ...|......::..:..||..:||||    .|...:..||..| .|.|.|. |.:|     |...
Worm   317 SSLDNLDQNDVRGAISEIEQKTCIRFKYFASPPKGNHINYQKV-NSPSFCGLSYIG-----RVEP 375

  Fly   130 LKPGSLDTGCFK-LGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGD 193
            ..|..|...|.. .|...||.:|.||.:||....:||:.:|:...||:......||..:......
Worm   376 ANPVYLSFQCGNGRGIAVHETMHALGVNHQHLRMDRDKHIKVDWSNINPQQYDAFVVADSKLYTT 440

  Fly   194 FDQPYDYGSILHYSSLAFSIN-GEATIVAL-NPEGQ-EQMGQRLMMSDTDVKRLNTMY 248
            :...|.|.||:||::...::| .:.|::.| |.:.. ..:|||..||:.||:.||.||
Worm   441 YGVKYAYDSIMHYNAYTGAVNIAKPTMIPLVNQQANIGLLGQRAKMSNADVEILNKMY 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	60/202 (30%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	56/196 (29%)
nas-10	NP_001257126.1	Astacin	303..501	CDD:396122	60/202 (30%)
nas-10	NP_001257126.1	ShK	503..540	CDD:396228
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020