DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and nas-15

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_508154.2	Gene:	nas-15 / 180426	WormBaseID:	WBGene00003534	Length:	571	Species:	Caenorhabditis elegans

Alignment Length:	268	Identity:	84/268 - (31%)
Similarity:	130/268 - (48%)	Gaps:	33/268 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FLLGTLCSGIFPAPFNTHYDETDPELTAGYFQGDMDVD---------YARNGQ------------ 52
            |.|||..:............::|...:...|:||:..|         :|..|.
Worm    52 FELGTRITAAMAHDNGDDIWDSDAMYSKDRFEGDIANDNLNASTAELFANGGSGKSEDGKWYNAI 116

  Fly    53 LSETRRWPNATVPYRISEEFDAPHVEYIKLGMQFIEYSS--CIRFVPADEDEENYLFVLPSTSGC 115
            .:..:.||...:||.||.::.:.....|...||  ||:|  |||:||.:..:.||:.:.|. .||
Worm   117 KNRLQLWPEGRIPYTISSQYSSYSRSLIAASMQ--EYASHTCIRWVPKEAADVNYVHIYPD-RGC 178

  Fly   116 SSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHE 180
            .|.||...|::::     ||.:||.:.|.|.|||:|.:||.|:|...:||:.:.|:..||..|.:
Worm   179 YSMVGKMGGKQSL-----SLGSGCIQKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQ 238

  Fly   181 KNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSINGEATIVALNPEGQEQMGQRLMMSDTDVKRLN 245
            ..|.||....:......||||||:||.:.|||.||:.|::.  .:....:|||...|..|..::|
Worm   239 GQFEKYGHGTIQSLGTGYDYGSIMHYGTKAFSRNGQPTMIP--KKNGATIGQRNGFSKVDKFKIN 301

  Fly   246 TMYKCPIQ 253
            |:|.||::
Worm   302 TLYGCPVE 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	71/195 (36%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	68/188 (36%)
nas-15	NP_508154.2	Astacin	121..308	CDD:279708	72/196 (37%)
		ZnMc_astacin_like	126..304	CDD:239807	68/187 (36%)
		ShKT	354..388	CDD:214586
		ShK	436..471	CDD:279838
		Gag_MA	<472..531	CDD:279482
		ShK	535..571	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920