DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and nas-38

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001359993.1	Gene:	nas-38 / 180407	WormBaseID:	WBGene00003554	Length:	727	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	68/249 - (27%)
Similarity:	105/249 - (42%)	Gaps:	29/249 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NT--HYDETDPELTAGYFQGDMDV---------DYARNGQLSET--------RRW-PNATVPYRI 68
            ||  |:||........|||||:|:         |....|:..:.        ::| ....:.:..
Worm    70 NTGVHHDELAVNNADEYFQGDVDLSEQQVKIIEDQFTQGKREKRKIGRNPLYKKWDTRGPISFDY 134

  Fly    69 SEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQPGERTVKLKPG 133
            :|.......:.|:..|...:..:|:||.....:.:...|.  ...||||.||...|.:.:
Worm   135 AESIPFQTRQKIRSAMLLWQQHTCLRFEEGGPNVDRLEFF--DGGGCSSFVGRVGGTQGI----- 192

  Fly   134 SLDT-GCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQP 197
            |:.| ||..:|.|.||:.|.||..|:|..|:::..:.|...||......||....|:....::.|
Worm   193 SISTPGCDVVGIISHEIGHALGIFHEQARPDQERHIAINYNNIPLSRWNNFQAVGENHAETYNLP 257

  Fly   198 YDYGSILHYSSLAFSING-EATIVALNPEGQEQMGQRLMMSDTDVKRLNTMYKC 250
            ||.||::||....|:.:. ..||..|....|..:|||...|..|.:.:|..|.|
Worm   258 YDTGSVMHYGPYGFASDPYTPTIRTLERVQQSTIGQRAGPSFLDYQAINMAYGC 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	55/197 (28%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	52/188 (28%)
nas-38	NP_001359993.1	Astacin	122..313	CDD:366617	55/197 (28%)
		CUB	367..466	CDD:214483
		TSP1	613..658	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920