DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and dpy-31

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001022731.1	Gene:	dpy-31 / 176014	WormBaseID:	WBGene00006592	Length:	592	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	83/253 - (32%)
Similarity:	122/253 - (48%)	Gaps:	38/253 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 DPELTAGYFQGDMDVDYARNGQL-------------------SETRRWPNATVPYRISEEFDAPH 76
            :||....:||||: |.|....:.                   |..||| :|:.|  |...||..|
Worm    90 NPEEQGKFFQGDI-VLYPEQAKALYEQALTEGKTRVKRKFIGSNLRRW-DASRP--IIYAFDGSH 150

  Fly    77 VE----YIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQP--GERTVKLKPGSL 135
            .:    .|:|.::.....:|:.|...|:.......|.....||:|.||..|  .|:.|.|.|
Worm   151 TQREQRIIELALEHWHNITCLNFQRNDQANSGNRIVFTDVDGCASNVGRHPLGEEQLVSLAP--- 212

  Fly   136 DTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDY 200
              .|.:||.|.||:.|.|||.|:|..|:||::|.:..|||.:..:..|:|.:.|:|.:...||||
Worm   213 --ECIRLGVIAHEVAHALGFWHEQSRPDRDQYVTVRWENIDKDSKGQFLKEDPDDVDNAGVPYDY 275

  Fly   201 GSILHYSSLAFS-INGEATIVALNPEGQEQMGQRLMMSDTDVKRLNTMY---KCPIQL 254
            |||:||.|.||| .:...||.....:.|:.:|||..:|..|::.:|.:|   .||.:|
Worm   276 GSIMHYRSKAFSKFDDLYTISTYVTDYQKTIGQRDQLSFNDIRLMNKIYCSAVCPSKL 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	71/203 (35%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	67/193 (35%)
dpy-31	NP_001022731.1	Astacin	134..327	CDD:279708	71/200 (36%)
		ZnMc_astacin_like	139..324	CDD:239807	66/191 (35%)
		CUB	383..483	CDD:214483
		TSP1	493..539	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020