DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and toh-1

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_497769.3	Gene:	toh-1 / 175491	WormBaseID:	WBGene00006591	Length:	414	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	55/213 - (25%)
Similarity:	98/213 - (46%)	Gaps:	26/213 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GQLSETRRWPNATVPYRI---SEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPST 112
            ||:.:   |.:..:|::|   ...|.:    .|:.|::..|.|:|:||....:..:...:||...
Worm    66 GQIYD---WNSYEIPFQIWGGDYNFQS----LIRRGIRMWEDSTCLRFKENQQSRDAIRYVLEKG 123

  Fly   113 SGCSSK-VGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENIS 176
            ..|.:: :|...|.:.:     .:.:.|.:...:.||..|.|||.|....|:||..:.|..:|:.
Worm   124 DSCFTEYIGRNGGHQDI-----IIGSECAEEYVVAHETGHALGFWHTHQRPDRDRHISINWKNVM 183

  Fly   177 EGHEKNFVKYEE-------DEVGDFDQPYDYGSILHYSSLAFSIN-GEATIVALNPEGQEQMGQR 233
            |....:|:.:..       .:|.....||||||::||.::|.::. .:.|||....:....||..
Worm   184 EEATASFMPFRSMLQAFGIRQVSPRRVPYDYGSLMHYHAVAHAVKVSDFTIVPKELKYVTTMGTE 248

  Fly   234 LMMSDTDVKRLNTMYKCP 251
             .|:..|.|.:|.:| ||
Worm   249 -KMAFLDAKVINDIY-CP 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	51/205 (25%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	49/198 (25%)
toh-1	NP_497769.3	Astacin	71..265	CDD:279708	53/205 (26%)
		ZnMc_astacin_like	73..262	CDD:239807	49/198 (25%)
		CUB	320..410	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820