DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and Mep1a

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_032611.2	Gene:	Mep1a / 17287	MGIID:	96963	Length:	760	Species:	Mus musculus

Alignment Length:	270	Identity:	85/270 - (31%)
Similarity:	123/270 - (45%)	Gaps:	32/270 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 IRVWFQLFLLGTLCSGIFPAP---------FNTHYDETDP---------ELTAG--YFQGDMDVD 46
            |.:|.|   ...|.|.||.|.         .|....:||.         .|.||  .||||:.:.
Mouse    13 IMLWIQ---PACLLSLIFSAHIAAVSIKHLLNGSDHDTDVGEQKDIFEINLAAGLNLFQGDILLP 74

  Fly    47 YARNGQLSETRRWPNATVPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPS 111
            ..||.....:.|| ...:||.:::..:......|....:.....||:.|.|. |.|.:|: :...
Mouse    75 RTRNAMRDPSSRW-KLPIPYILADNLELNAKGAILHAFEMFRLKSCVDFKPY-EGESSYI-IFQK 136

  Fly   112 TSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENIS 176
            .|||.|.:|.|...:.:     |:..||....||:||:||.|||.|:|...:||::|.|..:.|.
Mouse   137 LSGCWSMIGDQQVGQNI-----SIGEGCDFKATIEHEILHALGFFHEQSRTDRDDYVNIWWDQII 196

  Fly   177 EGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSINGE-ATIVALNPEGQEQMGQRLMMSDTD 240
            ..:|.||..|:::.:.|.:.||||.|::||...:|:.|.. .||....||....:||....|..|
Mouse   197 TDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSFNKNESIPTITTKIPEFNTIIGQLPDFSAID 261

  Fly   241 VKRLNTMYKC 250
            :.|||.||.|
Mouse   262 LIRLNRMYNC 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	65/195 (33%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	60/187 (32%)
Mep1a	NP_032611.2	ZnMc	46..271	CDD:381785	75/232 (32%)
		MAM	281..444	CDD:366209
		MATH	443..607	CDD:351761
		EGF	688..722	CDD:333761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910