DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7631 and nas-36

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_492109.2	Gene:	nas-36 / 172506	WormBaseID:	WBGene00003552	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	67/229 - (29%)
Similarity:	108/229 - (47%)	Gaps:	25/229 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FQGDM------DVDYARNGQLSETRR------------WPNATVPYRISEEFDAPHVEYIKLGMQ 85
            |:||:      .||..:.....:|:|            |....:.||..|..|...:..|...::
Worm    98 FEGDIFLSRRQAVDILKALSKDKTKRLRRSFVSDKTATWKTMPIKYRFHESIDFYTISQIIAAIR 162

  Fly    86 FIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELL 150
            |.|.|:||.|....:..:.......|..||.|.:|...|.:.:     |:...|.|:|.|:||:.
Worm   163 FWEDSTCITFENVSDSPDGDYIEFFSGQGCYSMIGRNGGRQGI-----SIGESCVKMGVIEHEIG 222

  Fly   151 HTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSING 215
            |.||..|:|..|:...:|.|..:.|...:..:|:: .:||:.....|||.||::||.|.|||::.
Worm   223 HALGLWHEQSRPDALGYVTIERDFILPSYISDFLQ-RDDEIDTLGIPYDLGSVMHYGSTAFSVDQ 286

  Fly   216 EA-TIVALNPEGQEQMGQRLMMSDTDVKRLNTMY 248
            :: |:|..:...|:.:|||..:|..||..:||.|
Worm   287 KSKTVVTRDSLYQQTIGQREKLSFYDVATINTAY 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	61/205 (30%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	58/187 (31%)
nas-36	NP_492109.2	Astacin	134..323	CDD:279708	60/193 (31%)
		ZnMc_astacin_like	140..320	CDD:239807	58/185 (31%)
		CUB	380..478	CDD:214483
		TSP1	510..556	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820