DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and astl2d.2

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_031756346.1	Gene:	astl2d.2 / 105947175	XenbaseID:	XB-GENE-22069740	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	75/219 - (34%)
Similarity:	116/219 - (52%)	Gaps:	17/219 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 QGDMDVDYARNGQLSETRRWPNAT----VPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADE 100
            |||:.|..:|:..:.....|..:.    |||.:.:::.:..:..|...|:.....:|::|||. .
Frog    80 QGDIAVRVSRSTIVCTDCFWQKSNGIVYVPYTLDKQYSSDQINTITSAMEVYSTLTCVQFVPY-T 143

  Fly   101 DEENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRD 165
            |||:|: .:.|..||.|.:|.|.|.:.|.::.|.    |...||..|||.|.|||.|:|...:||
Frog   144 DEEDYI-AITSGDGCWSYMGRQGGAQVVSVEKGY----CTSEGTTMHELNHALGFVHEQSRSDRD 203

  Fly   166 EFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFS-INGEATIVA-LNPEGQE 228
            .:|.|:.:.||.|...||.|.   |..:.:..|||.||:||.:.||| ..|:.|||| |||  ..
Frog   204 NYVDIMYQYISPGDIVNFKKM---ETNNLNTTYDYHSIMHYPAWAFSNTTGQNTIVAKLNP--NT 263

  Fly   229 QMGQRLMMSDTDVKRLNTMYKCPI 252
            .:|....|::.|:.::|.:|:|.:
Frog   264 PLGPGSTMTNLDITKINRLYQCDV 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	69/199 (35%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	67/192 (35%)
astl2d.2	XP_031756346.1	ZnMc	103..285	CDD:412141	68/192 (35%)
		CUB	288..399	CDD:238001	75/219 (34%)
		CUB	402..513	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010