DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and LOC105946018

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_031756313.1	Gene:	LOC105946018 / 105946018	-ID:	-	Length:	583	Species:	Xenopus tropicalis

Alignment Length:	264	Identity:	77/264 - (29%)
Similarity:	120/264 - (45%)	Gaps:	45/264 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 FNTHYDETDPELTAGYFQG----------------------------DMDVDYARNGQLSETRRW 59
            ::..||....||...:.:|                            |:.|..:|:...|....|
Frog    96 YSLGYDHQKRELCVSFLEGKSDPFGQGDVFSRILKANQGNGVPRVQEDIAVGVSRSAITSTECLW 160

  Fly    60 --PNAT--VPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADEDEENYLFVLPSTSGCSSKVG 120
              .|.|  |||.:..::....|..:...|:.....:|::|||. .||::|:.: .|..||.|.:|
Frog   161 QKTNETVYVPYTLDSKYSNSEVNTMTSAMEVYATLTCVQFVPY-TDEDDYVNI-TSGDGCWSYMG 223

  Fly   121 YQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRDEFVKIVEENISEGHEKNFVK 185
            .|.|.:.|.::.|.    |...||..|||.|.|||.|:....:||.:|.|:.:.||.|   :.|.
Frog   224 RQGGAQVVSVEKGY----CTSEGTTMHELNHALGFVHEHSRSDRDNYVNIMYQYISPG---DIVN 281

  Fly   186 YEEDEVGDFDQPYDYGSILHYSSLAFS-INGEATIVA-LNPEGQEQMGQRLMMSDTDVKRLNTMY 248
            :|.....:.:..|||.||:||.:.||| ..|:.|||| |||  ...:|....|:..|:.::|.:|
Frog   282 FEIMNTNNLNTIYDYRSIMHYPAWAFSNTTGKNTIVAKLNP--NIIIGAGSTMTSLDIIKINRLY 344

  Fly   249 KCPI 252
            :|.:
Frog   345 ECDV 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	67/199 (34%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	65/190 (34%)
LOC105946018	XP_031756313.1	C2	92..>113	CDD:417471	4/16 (25%)
		ZnMc	164..346	CDD:412141	66/192 (34%)
		CUB	349..458	CDD:395345	77/264 (29%)
		CUB	463..574	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020