DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and astl3a.3

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_031746774.1	Gene:	astl3a.3 / 100498584	XenbaseID:	XB-GENE-22069675	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	84/219 - (38%)
Similarity:	122/219 - (55%)	Gaps:	15/219 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FQGDMDVDYARNGQLSETRRWPNAT-----VPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPA 98
            :|||:.....|:........||.:|     |||..|..:.|..:...|..||..|..:|:||||.
Frog    96 YQGDILRPKGRSAMNCTECLWPKSTDGTVIVPYNFSSNYSADQLALFKSTMQEYESLTCVRFVPR 160

  Fly    99 DEDEENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPN 163
             .:|.::|.:: |.:||:|.:|...|::||:|.    ..||...|.|||||.|.|||:|:|...:
Frog   161 -ANETDFLSIV-SDNGCASFLGKVGGDQTVQLD----SYGCIYRGIIQHELNHALGFYHEQSRSD 219

  Fly   164 RDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFSINGEATIVALNPEGQE 228
            ||::|.|..|||..|:|.||.|.:.:.:|   ..|||.|::|||..|||.||..|||. .|:...
Frog   220 RDDYVTIHTENIIPGYEGNFNKADSNNLG---LEYDYSSVMHYSGDAFSKNGNLTIVP-KPDPTV 280

  Fly   229 QMGQRLMMSDTDVKRLNTMYKCPI 252
            .:|||..:|..||.::|.:|:|.:
Frog   281 PIGQRDGLSILDVSKINRLYQCDV 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	79/198 (40%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	76/191 (40%)
astl3a.3	XP_031746774.1	ZnMc_hatching_enzyme	121..302	CDD:239810	76/190 (40%)
		CUB	306..414	CDD:238001
		CUB	419..527	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010