DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and astl2d.5

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_031756347.1	Gene:	astl2d.5 / 100495579	XenbaseID:	XB-GENE-22069752	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	218	Identity:	72/218 - (33%)
Similarity:	111/218 - (50%)	Gaps:	15/218 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 QGDMDVDYARNGQLSETRRW--PNAT--VPYRISEEFDAPHVEYIKLGMQFIEYSSCIRFVPADE 100
            |.|:.|..:|:........|  .|.|  |||.:.:::....|..:...|:.....:|::|||. .
Frog    60 QEDIAVGVSRSAITYTECLWQKTNGTVYVPYTLDDKYSNSEVNTMTSAMEVYATLTCVQFVPY-T 123

  Fly   101 DEENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTLGFHHQQCSPNRD 165
            ||::|:.: .|..||.|.:|.|.|.:.|.::.|.    |...||..|||.|.|||.|:|...:||
Frog   124 DEDDYVNI-TSGDGCWSYMGRQRGAQVVSVEKGY----CTSEGTTMHELNHALGFVHEQSRSDRD 183

  Fly   166 EFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAFS-INGEATIVALNPEGQEQ 229
            .:|.|:.:.||.|....|.|.|.:.:|   ..|||.|::||.:.||| ..|:.|||| .|.....
Frog   184 NYVNIMYQYISPGDVAEFKKMESNNLG---TTYDYRSVMHYPAWAFSNTTGQNTIVA-KPNPNII 244

  Fly   230 MGQRLMMSDTDVKRLNTMYKCPI 252
            :|....|:..|:.::|.:|:|.:
Frog   245 IGAGNTMTSLDIIKINRLYECDV 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	67/198 (34%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	65/189 (34%)
astl2d.5	XP_031756347.1	ZnMc	83..265	CDD:412141	66/191 (35%)
		CUB	268..377	CDD:395345	72/218 (33%)
		CUB	382..493	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010