DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7631 and astl2f

DIOPT Version :9

Sequence 1:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_002934133.3	Gene:	astl2f / 100495416	XenbaseID:	XB-GENE-22069764	Length:	624	Species:	Xenopus tropicalis

Alignment Length:	230	Identity:	81/230 - (35%)
Similarity:	114/230 - (49%)	Gaps:	16/230 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ETDPELTAGYFQGDMDVDYARNGQLSETRRWPNAT-----VPYRISEEFDAPHVEYIKLGMQFIE 88
            |.:.:......|||:.....|:.....:..||.||     |||.|:..||....|.|:..:..:.
Frog   173 EANKDTNVPLVQGDILEKLGRSTTNCTSCLWPRATSGLVNVPYTIASVFDDSEQELIQGALNELM 237

  Fly    89 YSSCIRFVPADEDEENYLFVLPSTSGCSSKVGYQPGERTVKLKPGSLDTGCFKLGTIQHELLHTL 153
            ..||||| .|...|.::| ...|.:||.|.||...|.:.|.:.    .:||...|.||||.||.|
Frog   238 TLSCIRF-KARTIETDFL-SFQSGNGCWSSVGKTGGSQEVSVS----KSGCMSHGIIQHETLHAL 296

  Fly   154 GFHHQQCSPNRDEFVKIVEENISEGHEKNFVKYEEDEVGDFDQPYDYGSILHYSSLAF-SINGEA 217
            ||.|:.|..:||.:|.|:.:.||||...:|.|...:.:|   ..|||.|::||....| :..|:|
Frog   297 GFIHEHCRSDRDNYVDIIYKYISEGDRSSFTKVNSNNLG---LQYDYSSVMHYGRFTFTNTPGQA 358

  Fly   218 TIVALNPEGQEQMGQRLMMSDTDVKRLNTMYKCPI 252
            ||:. .|:....:|||..:|..||.:||.:|.|.|
Frog   359 TIIP-KPDLSVPIGQRYGVSSLDVAKLNKLYNCNI 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	74/199 (37%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	71/192 (37%)
astl2f	XP_002934133.3	ZnMc	209..390	CDD:412141	70/190 (37%)
		CUB	394..504	CDD:238001
		CUB	507..621	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100