DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11865 and TLL2

DIOPT Version :9

Sequence 1:NP_609759.1 Gene:CG11865 / 34917 FlyBaseID:FBgn0028947 Length:240 Species:Drosophila melanogaster
Sequence 2:NP_036597.1 Gene:TLL2 / 7093 HGNCID:11844 Length:1015 Species:Homo sapiens


Alignment Length:200 Identity:70/200 - (35%)
Similarity:102/200 - (51%) Gaps:8/200 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 RVVKSWSEYYWKGRTLVYSYAGGFSSLDIASIESAMAEISSKTCVKF-RRTEYKREPQVVIQKEG 109
            |...|.:|..|.|..:.|...|.|:....|..:.||......|||.| .||:  .|..:|.....
Human   149 RATTSRTERIWPGGVIPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIERTD--EESFIVFSYRT 211

  Fly   110 SGCWSYVGYLGRADQTLNLGSGCMSNRTIQHELLHALGFFHTHSDPQRDKYVRIQTDNIRSGHEH 174
            .||.||||..|...|.:::|..|.....:.|||.|.:||:|.|:.|.||::|.|..:||:.|.|:
Human   212 CGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEY 276

  Fly   175 NFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKN-GQSTIVPLKS----HAKIGQATQMSPKDVQT 234
            ||.::.|..|::.|..||:||||||....||:. ...||:|.:.    ...|||..::|..|:..
Human   277 NFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQ 341

  Fly   235 LKRMY 239
            .:::|
Human   342 ARKLY 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11865NP_609759.1 Astacin 56..239 CDD:279708 66/188 (35%)
ZnMc_astacin_like 58..239 CDD:239807 65/186 (35%)
TLL2NP_036597.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..49
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 88..130
ZnMc_BMP1_TLD 150..349 CDD:239808 68/198 (34%)
Astacin 157..350 CDD:279708 66/191 (35%)
CUB 351..460 CDD:278839
CUB 464..573 CDD:278839
FXa_inhibition 584..616 CDD:291342
CUB 620..729 CDD:278839
FXa_inhibition 736..771 CDD:291342
CUB 776..885 CDD:278839
CUB 889..1002 CDD:278839
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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