DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and mep1a.1

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001025452.1	Gene:	mep1a.1 / 553530	ZFINID:	ZDB-GENE-041001-209	Length:	598	Species:	Danio rerio

Alignment Length:	229	Identity:	83/229 - (36%)
Similarity:	120/229 - (52%)	Gaps:	23/229 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EDD-----IILISEQLQYFEGNL---EGRVVKSWSEYYWKGRTLVYSYAGGFSSLDI---ASIES 79
            ||:     .|.:..:.:..||::   .||:....:.|.|| ..:.|..:   .|||:   .:|..
Zfish    29 EDEPNFNPFINLGAKTRLIEGDIALPPGRIGLINTTYRWK-FPIPYILS---DSLDLNAKGAIYQ 89

  Fly    80 AMAEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVGYLGRADQTLNLGSGCMSNRTIQHELLH 144
            |......|:||.|:  .|:.|...:..::|.||||:||. .:..|.|:||.||.....|:|||||
Zfish    90 AFEVYRLKSCVDFK--PYEGEKTYIKFEKGDGCWSFVGD-QQNGQVLSLGPGCDHKAVIEHELLH 151

  Fly   145 ALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKNGQ 209
            ||||:|..|...||.||:|..|.:..|.||||.:...:.||:....|||:|:|||.||||:|:..
Zfish   152 ALGFYHMQSRQDRDDYVKIWLDQVIEGLEHNFNKYDDSFVTDLNTPYDYESVMHYRPFAFNKDPS 216

  Fly   210 ----STIVPLKSHAKIGQATQMSPKDVQTLKRMY 239
                :|.:| :.:..|||....|..|:..|.|||
Zfish   217 IPTITTNIP-EFYKIIGQYLDFSEMDIVRLNRMY 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	73/189 (39%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	71/187 (38%)
mep1a.1	NP_001025452.1	ZnMc	26..251	CDD:294052	83/229 (36%)
		Astacin	65..253	CDD:279708	76/193 (39%)
		MAM	261..420	CDD:279023
		MAM	261..419	CDD:99706
		MATH	419..582	CDD:295307
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010