DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and nas-39

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001360030.1	Gene:	nas-39 / 3565986	WormBaseID:	WBGene00003555	Length:	928	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	69/212 - (32%)
Similarity:	106/212 - (50%)	Gaps:	13/212 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 QYFEGNLEGRVVKSWS---EYYWKGRTLVYSYAGGFSSLDIASIESAMAEISSKTCVKF--RRTE 96
            :|:..|  |||.::.:   |..|....:.:..|..||.........||....:.|||.|  |:..
Worm    37 RYYRNN--GRVSRAATAKKERIWPEGIIPFVIASNFSGEHQHLFLRAMRHWENFTCVSFVPRQPH 99

  Fly    97 YKREPQVVIQKEGSGCWSYVGYLGRADQTLNLGSGCMSNRTIQHELLHALGFFHTHSDPQRDKYV 161
            :|......:.|  .||.||||..|...|.:::|..|.....:.|||.|.:||:|.|:.|.||.||
Worm   100 HKHYITFTVDK--CGCCSYVGRRGEGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDMYV 162

  Fly   162 RIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKNG-QSTIVPLKS---HAKIG 222
            .|...:|::|.::||::.:...|.:.|..||:.|||||....||:.. ..||:|..:   ..:||
Worm   163 DIFYKSIQTGQDYNFEKSKPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNSGFRLEIG 227

  Fly   223 QATQMSPKDVQTLKRMY 239
            |..|:|..|::..|::|
Worm   228 QRVQLSEGDIRQTKKLY 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	62/188 (33%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	61/186 (33%)
nas-39	NP_001360030.1	ZnMc_BMP1_TLD	48..247	CDD:239808	64/199 (32%)
		CUB	268..343	CDD:214483
		CUB	359..474	CDD:238001
		FXa_inhibition	480..515	CDD:373209
		CUB	519..622	CDD:366096
		FXa_inhibition	629..664	CDD:373209
		CUB	669..780	CDD:238001
		CUB	782..898	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810