DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11865 and mep1bb

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_009294699.1	Gene:	mep1bb / 327586	ZFINID:	ZDB-GENE-030131-5797	Length:	774	Species:	Danio rerio

Alignment Length:	227	Identity:	79/227 - (34%)
Similarity:	114/227 - (50%)	Gaps:	20/227 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EDDIILISEQ--LQYFEGNL-----EGRVVKSWSEYYWKGRTLVYSYAGGFSSLDIAS---IESA 80
            ::|:..::|.  |..|||::     .||......||.|. :|:.|.:.   ..|:|.:   |..|
Zfish    46 KEDLFDVNEDAGLDLFEGDILYDETLGRNSIIGEEYRWP-KTIPYYFE---DDLEINAKGVILKA 106

  Fly    81 MAEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVGYLGRADQTLNLGSGCMSNRTIQHELLHA 145
            ..:...|||:.::  .:..|...:...:|:||:|.||......|||::||||....||:||.|||
Zfish   107 FEQYRLKTCIDYK--PWTGEENYISVFKGNGCFSSVGNRRVGRQTLSIGSGCDRIATIEHEFLHA 169

  Fly   146 LGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKNGQS 210
            |||:|..|...||.||.|..|.|..|.||||.:...:..:.....|||.|:|||...||....:.
Zfish   170 LGFWHEQSRSDRDDYVSIMWDRITEGKEHNFNKYNDSSSSALNVPYDYSSMMHYSQKAFQSGSEP 234

  Fly   211 TI---VPLKSHAKIGQATQMSPKDVQTLKRMY 239
            ||   :|..| :.|||..:.|..|:..|.|:|
Zfish   235 TIITRIPAFS-SVIGQRMEFSDSDLLKLNRLY 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	68/188 (36%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	67/186 (36%)
mep1bb	XP_009294699.1	ZnMc	39..267	CDD:294052	79/227 (35%)
		Astacin	81..269	CDD:279708	70/192 (36%)
		MAM	277..441	CDD:279023
		MAM	277..440	CDD:99706
		MATH	440..608	CDD:295307
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910