DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and Mep1b

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_037315.1	Gene:	Mep1b / 25727	RGDID:	3081	Length:	704	Species:	Rattus norvegicus

Alignment Length:	222	Identity:	77/222 - (34%)
Similarity:	105/222 - (47%)	Gaps:	11/222 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EDDIILISEQ--LQYFEGNLE----GRVVKSWSEYYWKGRTLVYSYAGGFSSLDIASIESAMAEI 84
            :.||..|:|.  |..|||:::    ||.......|.|. .|:.|.............|.:|....
  Rat    36 DQDIFDINEDLGLDLFEGDIKLEASGRNSIIGDNYRWP-HTIPYVLEDSLEMNAKGVILNAFERY 99

  Fly    85 SSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVGYLGRADQTLNLGSGCMSNRTIQHELLHALGFF 149
            ..|||:.|:  .:..|...:...:||||||.||.:....|.|::|:.|....|:|||.||||||:
  Rat   100 RLKTCIDFK--PWSGEENYISVFKGSGCWSSVGNIHAGKQELSIGTNCDRIATVQHEFLHALGFW 162

  Fly   150 HTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKNGQSTIVP 214
            |..|...||.|:.|..|.|.||.||||.....:...:....|||.|:|||...||....:|||:.
  Rat   163 HEQSRADRDDYITIVWDRILSGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQNGTESTIIT 227

  Fly   215 LKSHAK--IGQATQMSPKDVQTLKRMY 239
            ..|..:  |||....|..|:..|.::|
  Rat   228 KISDFEDVIGQRMDFSDYDLLKLNQLY 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	65/184 (35%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	64/182 (35%)
Mep1b	NP_037315.1	ZnMc	30..256	CDD:294052	77/222 (35%)
		Astacin	70..258	CDD:279708	67/188 (36%)
		MAM	266..430	CDD:279023
		MAM	266..428	CDD:99706
		MATH	428..586	CDD:295307
		EGF_CA	609..647	CDD:238011
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910