DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11865 and Mep1a

DIOPT Version :9

Sequence 1:NP_609759.1 Gene:CG11865 / 34917 FlyBaseID:FBgn0028947 Length:240 Species:Drosophila melanogaster
Sequence 2:NP_037275.1 Gene:Mep1a / 25684 RGDID:3080 Length:748 Species:Rattus norvegicus


Alignment Length:229 Identity:83/229 - (36%)
Similarity:120/229 - (52%) Gaps:24/229 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 QEDDIILISEQ--LQYFEGNL---EGRVVKSWSEYYWKGRTLVYSYAGGFSSLDI---ASIESAM 81
            |:.||..|:..  |..|:|::   ..|.........|| ..:.|..|   .:||:   .:|.:|.
  Rat    40 QQKDISEINSAAGLNLFQGDILLPRTRNALRDPSSRWK-PPIPYILA---DNLDLNAKGAILNAF 100

  Fly    82 AEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVG--YLGRADQTLNLGSGCMSNRTIQHELLH 144
            .....|:||.|:  .|:.|...:|.::.|||||.||  ::|   |.:::|.||.....|:||:||
  Rat   101 EMFRLKSCVDFK--PYEGESSYIIFQQFSGCWSMVGDQHVG---QNISIGEGCDYKAIIEHEILH 160

  Fly   145 ALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKNGQ 209
            ||||||..|...||.||.|..:.|.:.:||||.......:|:....|||:|:||||||:|:||..
  Rat   161 ALGFFHEQSRTDRDDYVNIWWNEIMTDYEHNFNTYDDKTITDLNTPYDYESLMHYGPFSFNKNET 225

  Fly   210 ----STIVPLKSHAKIGQATQMSPKDVQTLKRMY 239
                :|.:| :.:|.|||....|..|:..|.|||
  Rat   226 IPTITTKIP-EFNAIIGQRLDFSATDLTRLNRMY 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11865NP_609759.1 Astacin 56..239 CDD:279708 73/191 (38%)
ZnMc_astacin_like 58..239 CDD:239807 71/189 (38%)
Mep1aNP_037275.1 ZnMc 32..260 CDD:294052 83/229 (36%)
Astacin 75..261 CDD:279708 75/194 (39%)
MAM 270..433 CDD:279023
MAM 270..432 CDD:99706
MATH 432..596 CDD:295307
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 641..668
EGF 676..710 CDD:278437
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10127
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.910

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