DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and nas-13

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_510549.3	Gene:	nas-13 / 185492	WormBaseID:	WBGene00003532	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	76/243 - (31%)
Similarity:	119/243 - (48%)	Gaps:	30/243 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 QEDDIILISEQLQY----FEGNLEGRVVKSWS----------------------EYY--WKGRTL 61
            :|:|...:::...|    |||::....:.|.|                      :.|  |:...:
Worm    60 RENDQWFVNDSAMYNPLRFEGDIANSGLNSRSINTFFGDSPLFGIFGVQRNAVRQTYLKWEQARI 124

  Fly    62 VYSYAGGFSSLDIASIESAMAEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVGYLGRADQTL 126
            .|:.:..:||...:.|..|:.|...|||:.|..........:.|..: .||:|.||.:| ..|.:
Worm   125 PYTISSQYSSYSRSKIAEAIEEYRKKTCIDFSPKSAGDLDYIHIVPD-DGCYSLVGRIG-GKQPV 187

  Fly   127 NLGSGCMSNRTIQHELLHALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGY 191
            :||.||:....|.|||:||:||||..|...||:||:|...|:.:|.:..|.:...|.:.:.|..|
Worm   188 SLGDGCIQKGIIIHELMHAVGFFHEQSRADRDEYVKINWSNVEAGLQDQFDKYSLNMIDHLGTKY 252

  Fly   192 DYDSIMHYGPFAFSKNGQSTIVPLKSHAKIGQATQMSPKDVQTLKRMY 239
            ||.|:|||.|.||||||:.||.|::.:.:|||....|..|:..:..:|
Worm   253 DYGSVMHYAPTAFSKNGKPTIEPIEKNVEIGQRAGFSENDIYKINMLY 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	66/182 (36%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	65/180 (36%)
nas-13	NP_510549.3	Astacin	118..304	CDD:279708	67/185 (36%)
		ZnMc_astacin_like	122..300	CDD:239807	65/179 (36%)
		ShK	367..404	CDD:279838
		ShK	414..450	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920