DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and nas-6

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001040902.1	Gene:	nas-6 / 181796	WormBaseID:	WBGene00003525	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	70/218 - (32%)
Similarity:	114/218 - (52%)	Gaps:	21/218 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FEGNLEG---------------RVVKSWSEYYWKGRTLVYSYAGGFSSLDIASIESAMAEISSKT 88
            |:|:::|               ..:|: .:..|:|..:.|.....||..:|..:|.|.......|
Worm    50 FQGDIDGVDPNLLKLPEGPVLFNALKN-KQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRRTT 113

  Fly    89 CVKFRRTEYKREPQVVIQKEGSGCWSYVGYLGRADQTLNLGSGCMSNRTIQHELLHALGFFHTHS 153
            |::|.:.|.:.:...::  :|.||:|.||..| ..|.::||.||..:..|.|||:|::||:|.||
Worm   114 CIRFEKREGQTDYLNIV--KGYGCYSQVGRTG-GKQEISLGRGCFFHEIIVHELMHSVGFWHEHS 175

  Fly   154 DPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKNGQSTIVPLKS- 217
            ...||.:::|..|||..|.:..|.::.|......|..|||.|||||...|||:||::||..:::
Worm   176 RADRDDHIKINWDNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENG 240

  Fly   218 -HAKIGQATQMSPKDVQTLKRMY 239
             ...||.|..:||.|:..:.::|
Worm   241 FTQVIGTAMDLSPLDIVKINKLY 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	65/184 (35%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	64/182 (35%)
nas-6	NP_001040902.1	Astacin	80..265	CDD:279708	66/187 (35%)
		ZnMc_astacin_like	83..263	CDD:239807	64/182 (35%)
		ShK	299..334	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950