DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and nas-11

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001024789.1	Gene:	nas-11 / 180938	WormBaseID:	WBGene00003530	Length:	579	Species:	Caenorhabditis elegans

Alignment Length:	214	Identity:	69/214 - (32%)
Similarity:	102/214 - (47%)	Gaps:	21/214 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 YFEGNLEGRVVKSWSEYYWKGRTLVYSYAGGFSSLDIASIESAMAEISSKTCVKFRRTEYKREP- 101
            ||||||    :|.|.    ....:.|........||...:.:|:.||...||::|:  |....|
Worm   332 YFEGNL----IKKWD----PSSPIRYVLDSSLEDLDKNDVRAAIYEIEKNTCIRFK--ELSSPPT 386

  Fly   102 --QVVIQKEGSGCWSYVGYLGRAD--QTLNLGSGCMSNRTIQ-HELLHALGFFHTHSDPQRDKYV 161
              .:|..|..|..:..:.|:||||  ..:.|..||.:|:.:. ||.:||||..|.|....||:::
Worm   387 GSHIVYYKVDSPTFCGLSYVGRADPANPVYLSFGCDNNKGVAIHETMHALGVAHQHLRNDRDQFI 451

  Fly   162 RIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKN-GQSTIVPLKSHA----KI 221
            .|...||.......|..:.:...|:||..|.|||||||..:..::| ...|:.|..:.|    .:
Worm   452 TINWSNIDPQQYDAFVVVDSKLYTSYGVKYAYDSIMHYNGYTAAQNIAIPTMNPKTNSAVNLKVL 516

  Fly   222 GQATQMSPKDVQTLKRMYC 240
            ||..:|...|::.||:|||
Worm   517 GQRQKMGTTDIELLKKMYC 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	58/193 (30%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	58/191 (30%)
nas-11	NP_001024789.1	Astacin	339..537	CDD:279708	63/203 (31%)
		ZnMc_astacin_like	346..534	CDD:239807	58/189 (31%)
		ShK	538..575	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020