DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and nas-15

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_508154.2	Gene:	nas-15 / 180426	WormBaseID:	WBGene00003534	Length:	571	Species:	Caenorhabditis elegans

Alignment Length:	184	Identity:	71/184 - (38%)
Similarity:	106/184 - (57%)	Gaps:	2/184 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 WKGRTLVYSYAGGFSSLDIASIESAMAEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVGYLG 120
            |....:.|:.:..:||...:.|.::|.|.:|.||:::...|......|.|..: .||:|.||.:|
Worm   123 WPEGRIPYTISSQYSSYSRSLIAASMQEYASHTCIRWVPKEAADVNYVHIYPD-RGCYSMVGKMG 186

  Fly   121 RADQTLNLGSGCMSNRTIQHELLHALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVT 185
             ..|:|:|||||:....|.|||:||:||||..|...||.::.|..:||::|.:..|::.....:.
Worm   187 -GKQSLSLGSGCIQKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQGQFEKYGHGTIQ 250

  Fly   186 NYGFGYDYDSIMHYGPFAFSKNGQSTIVPLKSHAKIGQATQMSPKDVQTLKRMY 239
            :.|.||||.||||||..|||:|||.|::|.|:.|.|||....|..|...:..:|
Worm   251 SLGTGYDYGSIMHYGTKAFSRNGQPTMIPKKNGATIGQRNGFSKVDKFKINTLY 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	70/182 (38%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	69/180 (38%)
nas-15	NP_508154.2	Astacin	121..308	CDD:279708	71/184 (39%)
		ZnMc_astacin_like	126..304	CDD:239807	69/179 (39%)
		ShKT	354..388	CDD:214586
		ShK	436..471	CDD:279838
		Gag_MA	<472..531	CDD:279482
		ShK	535..571	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920