DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and dpy-31

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001022731.1	Gene:	dpy-31 / 176014	WormBaseID:	WBGene00006592	Length:	592	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	75/237 - (31%)
Similarity:	116/237 - (48%)	Gaps:	26/237 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KLQEDDIILISEQLQ--YFEGNLEGRV----------VKSWSEYYWKGRTLVYSYAGGFSSLDIA 75
            |..:.||:|..||.:  |.:...||:.          ::.|.    ..|.::|::.|..:..:..
Worm    96 KFFQGDIVLYPEQAKALYEQALTEGKTRVKRKFIGSNLRRWD----ASRPIIYAFDGSHTQREQR 156

  Fly    76 SIESAMAEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVGY--LGRADQTLNLGSGCMSNRTI 138
            .||.|:....:.||:.|:|.:.......::..:..||.|.||.  ||. :|.::|...|:....|
Worm   157 IIELALEHWHNITCLNFQRNDQANSGNRIVFTDVDGCASNVGRHPLGE-EQLVSLAPECIRLGVI 220

  Fly   139 QHELLHALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFA 203
            .||:.|||||:|..|.|.||:||.::.:||....:..|.:...:.|.|.|..|||.|||||...|
Worm   221 AHEVAHALGFWHEQSRPDRDQYVTVRWENIDKDSKGQFLKEDPDDVDNAGVPYDYGSIMHYRSKA 285

  Fly   204 FSKNGQ----STIVPLKSHAK-IGQATQMSPKDVQTLKRMYC 240
            |||...    ||.|  ..:.| |||..|:|..|::.:.::||
Worm   286 FSKFDDLYTISTYV--TDYQKTIGQRDQLSFNDIRLMNKIYC 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	63/189 (33%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	63/187 (34%)
dpy-31	NP_001022731.1	Astacin	134..327	CDD:279708	66/199 (33%)
		ZnMc_astacin_like	139..324	CDD:239807	63/187 (34%)
		CUB	383..483	CDD:214483
		TSP1	493..539	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020