DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and astl2d.4

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_004913426.2	Gene:	astl2d.4 / 101734297	XenbaseID:	XB-GENE-22069748	Length:	537	Species:	Xenopus tropicalis

Alignment Length:	260	Identity:	85/260 - (32%)
Similarity:	123/260 - (47%)	Gaps:	42/260 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IFGLG-------SSANGRPSIKLQEDDIILISE-----QLQYFEGNLEGRVVKS--------WSE 53
            ||||.       .|..|:.:|...:|....::|     :::..:|::...|.:|        |.:
Frog    57 IFGLDDVFSRLTESNTGQNAIFGPDDGFSRLTEANKGSRVRRVQGDIAIGVSRSALNCTNCLWPK 121

  Fly    54 YYWKGRTLV-YSYAGGFSSLDIASIESAMAEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVG 117
              ..|...| |:....:|:.::.:|.:||...::.|||:|  ..|..|...|..|..:|||||:|
Frog   122 --TNGTVYVPYTLDDEYSNNEVNTITAAMQVYATLTCVQF--VPYTDEDDYVAIKSANGCWSYMG 182

  Fly   118 YLGRADQTLNLGSG-CMSNRTIQHELLHALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRA 181
            ..|.| |.:::..| |.|..|..|||.|||||.|..|...||.||.|....|..|...||:.:..
Frog   183 RQGGA-QVVSVEKGYCTSEGTTMHELNHALGFVHEQSRSDRDNYVNIMYQYISPGDIVNFEIMNT 246

  Fly   182 NGVTNYGFGYDYDSIMHYGPFAFSK-NGQSTIVPLKSHAK------IGQATQMSPKDVQTLKRMY 239
            |.:...   |||.|||||..:|||. .||:|||     ||      ||..:.|:..|:..:.|:|
Frog   247 NNLNTI---YDYRSIMHYPAWAFSNTTGQNTIV-----AKPNPNIIIGAGSTMTSLDIIKINRLY 303

Fly 240 239
Frog 304 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	71/191 (37%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	71/189 (38%)
astl2d.4	XP_004913426.2	ZnMc_hatching_enzyme	123..305	CDD:239810	72/192 (38%)
		CUB	308..417	CDD:395345
		CUB	422..533	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010