DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11865 and astl2d.5

DIOPT Version :9

Sequence 1:	NP_609759.1	Gene:	CG11865 / 34917	FlyBaseID:	FBgn0028947	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_031756347.1	Gene:	astl2d.5 / 100495579	XenbaseID:	XB-GENE-22069752	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	84/249 - (33%)
Similarity:	117/249 - (46%)	Gaps:	42/249 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FGLGS------SAN-GRPSIKLQEDDIILISEQLQYFEGNLEGRVVKSWSEYYWK---GRTLV-Y 63
            ||.|.      .|| |....::|||..:.:|            |...:::|..|:   |...| |
Frog    38 FGQGHVFSRILKANQGNRVPRVQEDIAVGVS------------RSAITYTECLWQKTNGTVYVPY 90

  Fly    64 SYAGGFSSLDIASIESAMAEISSKTCVKFRRTEYKREPQVVIQKEGSGCWSYVGYLGRADQTLNL 128
            :....:|:.::.::.|||...::.|||:|  ..|..|...|....|.|||||:| ..|..|.:::
Frog    91 TLDDKYSNSEVNTMTSAMEVYATLTCVQF--VPYTDEDDYVNITSGDGCWSYMG-RQRGAQVVSV 152

  Fly   129 GSG-CMSNRTIQHELLHALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYD 192
            ..| |.|..|..|||.|||||.|..|...||.||.|....|..|....|:::.:|   |.|..||
Frog   153 EKGYCTSEGTTMHELNHALGFVHEQSRSDRDNYVNIMYQYISPGDVAEFKKMESN---NLGTTYD 214

  Fly   193 YDSIMHYGPFAFSK-NGQSTIVPLKSHAK------IGQATQMSPKDVQTLKRMY 239
            |.|:|||..:|||. .||:|||     ||      ||....|:..|:..:.|:|
Frog   215 YRSVMHYPAWAFSNTTGQNTIV-----AKPNPNIIIGAGNTMTSLDIIKINRLY 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11865	NP_609759.1	Astacin	56..239	CDD:279708	71/194 (37%)
CG11865	NP_609759.1	ZnMc_astacin_like	58..239	CDD:239807	70/189 (37%)
astl2d.5	XP_031756347.1	ZnMc	83..265	CDD:412141	71/192 (37%)
		CUB	268..377	CDD:395345
		CUB	382..493	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010