DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and bmp1a

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001035126.1	Gene:	bmp1a / 572452	ZFINID:	ZDB-GENE-060818-1	Length:	986	Species:	Danio rerio

Alignment Length:	235	Identity:	82/235 - (34%)
Similarity:	111/235 - (47%)	Gaps:	20/235 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SIRIETDPELTAGYIEGDMVPSGSSRNIWRNETYR----WPNRIIYYHINSYIDEEHRNHIVSAI 82
            |:..||....||.        |..|....|..|.|    ||..:|.|.|:.......|.....|:
Zfish    88 SLSNETSVNTTAS--------SRGSHRRRRAATSRPERVWPEGVIPYVISGNFSGSQRAIFRQAM 144

  Fly    83 QKIESISCLTFKEATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEF 147
            :..|..:|:||.|.||::.|.| .|....||.||:|....    ..|...||..|.:...:|||.
Zfish   145 RHWEKHTCVTFIERTTEESYIV-FTYRPCGCCSYVGRRGG----GPQAISIGKNCDKFGIVVHEL 204

  Fly   148 LHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKN 212
            .|.:||:|:.:..|||::|.|:.:||..|.|:||.|.....|:..||.||:.|:|||....||:.
Zfish   205 GHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLKMEPGEVDSLGEVYDFDSIMHYARNTFSRG 269

  Fly   213 -GERTILALEE--GKEDVIGQRLELSETDIRKLNAIYKCP 249
             ...|||...:  |....||||..||:.||.:...:||||
Zfish   270 IFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCP 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	73/202 (36%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	66/189 (35%)
bmp1a	NP_001035126.1	ZnMc_BMP1_TLD	112..309	CDD:239808	72/201 (36%)
		Astacin	117..309	CDD:279708	70/196 (36%)
		CUB	311..420	CDD:278839
		CUB	424..533	CDD:278839
		FXa_inhibition	544..576	CDD:291342
		CUB	580..699	CDD:278839
		FXa_inhibition	706..741	CDD:291342
		CUB	746..855	CDD:278839
		CUB	859..972	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810