DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and cuzd1.2

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_021323075.1	Gene:	cuzd1.2 / 555768	ZFINID:	ZDB-GENE-131119-30	Length:	718	Species:	Danio rerio

Alignment Length:	223	Identity:	41/223 - (18%)
Similarity:	68/223 - (30%)	Gaps:	88/223 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 PNRIIYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEATTDQKYYVN--------------VTS 108
            ||...|||.|:|                    |:.:..|...|:.::.              :|.
Zfish   343 PNYPSYYHDNAY--------------------CVWYLSAQQGQRIFLTFADVQLERCCDCDYITI 387

  Fly   109 EEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENI 173
            .:|   |..||           .::|..||...|  |:      .||..|.     |:.:|..:.
Zfish   388 HDG---SSTGY-----------PQLGNVCFNDTT--HQ------AFHSTSR-----YLTVVFRSD 425

  Fly   174 TEGMEFNFD-KYTEETVNDFGEKYDYGSVMHYGPYAFSKNGERTILALE---------EGKEDVI 228
            ..|:...|. .:|.....|.| :.|..|             :..::.|.         .|.:..:
Zfish   426 FSGVSHGFKAHFTSSLTADQG-RVDCSS-------------DNMVIVLRRSYLNSLGFSGNDLYV 476

  Fly   229 GQRL---ELSETDIRKLNAIYKCPTVKE 253
            ..||   .:|.|::.....:..|.|.|:
Zfish   477 DDRLCRPNISSTEVVFRFPLNTCGTAKK 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	39/218 (18%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	37/213 (17%)
cuzd1.2	XP_021323075.1	CUB	21..127	CDD:238001
		Somatomedin_B	131..164	CDD:307259
		Somatomedin_B	175..214	CDD:321959
		Somatomedin_B	<239..260	CDD:307259
		CUB	330..439	CDD:238001	27/142 (19%)
		ZP	450..694	CDD:214579	10/68 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900