DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and tll2l

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001016661.1	Gene:	tll2l / 549415	XenbaseID:	XB-GENE-478930	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	171	Identity:	64/171 - (37%)
Similarity:	90/171 - (52%)	Gaps:	9/171 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IVSAIQKIESISCLTFKEATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYT 142
            |.:|:|:.|:::|:.| ...|::|..:|: :...||:||||....|||::|...    .|.....
Frog   107 ITAAMQEFETLTCVDF-VPKTNEKNVINI-NNGNGCWSYIGRSGGVQQVSLSKQ----SCMVKGI 165

  Fly   143 IVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPY 207
            |.||..|.|||.|:...:|||.||.:|::||......|||   ....|:.|..|||.|||||...
Frog   166 IQHELNHVLGFVHEHVRSDRDQYVNVVKKNILPDSLGNFD---IAVTNNLGLPYDYYSVMHYPRN 227

  Fly   208 AFSKNGERTILALEEGKEDVIGQRLELSETDIRKLNAIYKC 248
            |||.:.....|..:......||||..|:..||.|:|.:|.|
Frog   228 AFSISPFLPTLITKPDPTIQIGQRYGLTNLDIAKINKLYNC 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	64/171 (37%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	62/167 (37%)
tll2l	NP_001016661.1	ZnMc_hatching_enzyme	86..268	CDD:239810	63/169 (37%)
		CUB	272..382	CDD:238001
		CUB	385..495	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020