DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and tll1

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001008039.1	Gene:	tll1 / 493401	XenbaseID:	XB-GENE-479941	Length:	495	Species:	Xenopus tropicalis

Alignment Length:	221	Identity:	73/221 - (33%)
Similarity:	112/221 - (50%)	Gaps:	21/221 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IEGDMVPSGSSRNIWRNETYRWP---NRIIY--YHINSYIDEEHRNHIVSAIQKIESISCLTFKE 95
            |.|| :...:.||........||   :..:|  |.::|...::..|.|.:|:::.|.::|:.|..
Frog    58 IHGD-IALKTDRNAINCTECLWPKSSDGFVYVPYTVSSDYSQDEVNAITTAMKEYEGLTCVQFTP 121

  Fly    96 ATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYT--IVHEFLHALGFFHQQS 158
            .|.:..|....:.:  ||:|||||....|.::|...      |..|.  :.||..|||||:|:.:
Frog   122 WTGEDDYLAIQSLD--GCWSYIGYYGGSQAVSLLKG------FCAYNGGVQHELNHALGFYHEHN 178

  Fly   159 AADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSK-NGERTILALEE 222
            .:||||||.|:.:.|:.....||||.   :.|:.|..|||.|::||...|||. :|:.||:. ..
Frog   179 RSDRDDYVTIMYQYISPENIGNFDKI---STNNLGVDYDYSSILHYAGNAFSNTSGQNTIVP-HP 239

  Fly   223 GKEDVIGQRLELSETDIRKLNAIYKC 248
            .....|||...||..|:.|:|.:|.|
Frog   240 NPNVPIGQSYGLSNLDVLKINRLYGC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	68/202 (34%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	64/191 (34%)
tll1	NP_001008039.1	ZnMc_hatching_enzyme	83..265	CDD:239810	65/193 (34%)
		CUB	269..379	CDD:238001
		CUB	382..494	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910