DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-39

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001360030.1	Gene:	nas-39 / 3565986	WormBaseID:	WBGene00003555	Length:	928	Species:	Caenorhabditis elegans

Alignment Length:	245	Identity:	79/245 - (32%)
Similarity:	121/245 - (49%)	Gaps:	10/245 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ILLLLLVVVNVAWAAPSIRIETDPELTAGYIEGDMVPSGSSRNIWRNETYRWPNRIIYYHINSYI 70
            |:.::.:.:.|.:..|:.....|......|.....|    ||.....:...||..||.:.|.|..
Worm    10 IVNIIFLFIVVEFVLPTFIRSGDVRFRRYYRNNGRV----SRAATAKKERIWPEGIIPFVIASNF 70

  Fly    71 DEEHRNHIVSAIQKIESISCLTFKEATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGV 135
            ..||::..:.|::..|:.:|::|.......|:|:..|.::.||.||:|....    ..|...||.
Worm    71 SGEHQHLFLRAMRHWENFTCVSFVPRQPHHKHYITFTVDKCGCCSYVGRRGE----GPQAISIGK 131

  Fly   136 GCFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGS 200
            .|.:...:|||..|.:||:|:.:..|||.||.|..::|..|.::||:|...|.|:..||.||:.|
Worm   132 NCDKFGIVVHELGHVVGFWHEHTRPDRDMYVDIFYKSIQTGQDYNFEKSKPEEVDSLGEPYDFSS 196

  Fly   201 VMHYGPYAFSKNG-ERTILAL-EEGKEDVIGQRLELSETDIRKLNAIYKC 248
            :|||....||:.. ..|||.. ..|....||||::|||.|||:...:|||
Worm   197 IMHYARDTFSRGAFYDTILPKPNSGFRLEIGQRVQLSEGDIRQTKKLYKC 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	71/196 (36%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	66/188 (35%)
nas-39	NP_001360030.1	ZnMc_BMP1_TLD	48..247	CDD:239808	71/203 (35%)
		CUB	268..343	CDD:214483
		CUB	359..474	CDD:238001
		FXa_inhibition	480..515	CDD:373209
		CUB	519..622	CDD:366096
		FXa_inhibition	629..664	CDD:373209
		CUB	669..780	CDD:238001
		CUB	782..898	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810