DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15253 and Tll2

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_036034.1	Gene:	Tll2 / 24087	MGIID:	1346044	Length:	1012	Species:	Mus musculus

Alignment Length:	215	Identity:	74/215 - (34%)
Similarity:	104/215 - (48%)	Gaps:	12/215 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SRNIWRNETYR----WPNRIIYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEATTDQKYYVNV 106
            |..:.|..|.|    ||..:|.|.|........|.....|::..|..:|:||.| .||::.::..
Mouse   141 SARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVE-RTDEESFIVF 204

  Fly   107 TSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEE 171
            :....||.||:|....    ..|...||..|.:...:.||..|.:||:|:.:..|||.:|.|:.|
Mouse   205 SYRTCGCCSYVGRRGG----GPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRE 265

  Fly   172 NITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKN-GERTILAL--EEGKEDVIGQRLE 233
            ||..|.|:||.|.....|:..||.||:.|:|||....||:. ...|||..  :.|....||||:.
Mouse   266 NIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVR 330

  Fly   234 LSETDIRKLNAIYKCPTVKE 253
            ||:.||.:...:||||...|
Mouse   331 LSQGDIAQARKLYKCPACGE 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	69/201 (34%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	63/189 (33%)
Tll2	NP_036034.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	83..135
		ZnMc_BMP1_TLD	147..346	CDD:239808	69/203 (34%)
		Astacin	154..347	CDD:279708	68/197 (35%)
		CUB	348..457	CDD:278839	1/3 (33%)
		CUB	461..570	CDD:278839
		FXa_inhibition	581..613	CDD:291342
		CUB	617..726	CDD:278839
		FXa_inhibition	733..768	CDD:291342
		CUB	773..882	CDD:278839
		CUB	886..999	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810