DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-33

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_509086.2	Gene:	nas-33 / 186987	WormBaseID:	WBGene00003551	Length:	644	Species:	Caenorhabditis elegans

Alignment Length:	234	Identity:	76/234 - (32%)
Similarity:	117/234 - (50%)	Gaps:	22/234 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ELTAGYIEGDMVPSGSSRNIWRNETYR-----------WPNRIIYYHINSYIDEEHRNHIVSAIQ 83
            ::.|...|.||..:.|..|......:|           |...|.|..:::  |...::.|.:.::
Worm   164 KIAAVMFESDMALTVSQMNKVAQNGFRVKRKMNLNGTTWSRNIPYRFLDT--DGNWQSQITNGLR 226

  Fly    84 KIESISCLTFKEATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFL 148
            ..|..:|:.|........|.  |.|:..||:|.:|.|...|:::     ||.||..|..|.||..
Worm   227 HYERNTCIRFSLNGGGSDYL--VFSKGEGCYSSVGRLGGPQEIS-----IGDGCETLGIITHEVG 284

  Fly   149 HALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKNG 213
            |||||:|:|:..:||.||:|..:|...|:|..|||.:...||::...|||||||||||.:|||:.
Worm   285 HALGFWHEQARPERDSYVRINRQNAINGLEGQFDKRSWSEVNEYSLPYDYGSVMHYGPKSFSKSS 349

  Fly   214 E-RTILALEEGKEDVIGQRLELSETDIRKLNAIYKCPTV 251
            . .|:..::....:.||.|:|.|..|::.||..: |..:
Worm   350 TMNTVEPVDPAFINTIGNRVEPSFLDLKLLNTAF-CSNI 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	70/206 (34%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	67/187 (36%)
nas-33	NP_509086.2	Astacin	200..386	CDD:279708	69/195 (35%)
		ZnMc_astacin_like	203..381	CDD:239807	66/186 (35%)
		CUB	442..527	CDD:294042
		TSP1	553..595	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920