DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-31

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001023994.1	Gene:	nas-31 / 186493	WormBaseID:	WBGene00003549	Length:	611	Species:	Caenorhabditis elegans

Alignment Length:	241	Identity:	76/241 - (31%)
Similarity:	115/241 - (47%)	Gaps:	44/241 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGDMV--------------------PSGSSRNIWRNETY---RWPNRIIYYHINSYIDEEHRNHI 78
            :||||                    .|.:.|..:|:..|   .|.:.:.||:     |......|
Worm   128 QGDMVLTDDQIATILEARDETTVSTASRARRQAYRDRYYPSTTWGSSVYYYY-----DRTATPKI 187

  Fly    79 VSAIQKI----ESISCLTFKEATTDQKYYVN-VTSEEG-GCFSYIGYLNRVQQLNLQNNEIGVGC 137
            |.|.::.    ::::|:...:::|    .:| :...:| ||:||:|.::.||.|:|     |.||
Worm   188 VKAFEQAVAFWQNVTCINIMQSST----AINRIRVFKGQGCYSYVGRISGVQDLSL-----GTGC 243

  Fly   138 FRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVM 202
            ....|..||..|||||||.||..|||:|:.|...||.......|||.|..|..::|..|||||:|
Worm   244 EEFGTAAHELGHALGFFHTQSRYDRDNYISINYANIDPSYVEQFDKETSNTNFNYGMPYDYGSIM 308

  Fly   203 HYGPYAFSKNGERTILALEEGKEDVIGQRLELSETDIRKLNAIYKC 248
            .||..:.|.|.:.|::|.:...:|.:|... :...||..:|..|||
Worm   309 QYGATSASSNDKATMIARDTEYQDTMGSDF-VGFYDISMMNEHYKC 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	69/203 (34%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	64/192 (33%)
nas-31	NP_001023994.1	Astacin	169..355	CDD:279708	68/200 (34%)
		ZnMc_astacin_like	175..351	CDD:239807	64/190 (34%)
		ShKT	532..564	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010